Naked mole rats live for decades -- genetic tweaks reveal insights into ageing

Research on the Naked mole-rat reveals that four genetic tweaks could explain the rodents extraordinary longevity, shedding light on DNA repair mechanisms and potential cancer resistance.

• The Naked mole-rat can live for nearly 30 years, a remarkable lifespan for a rodent of its size, prompting studies into its unique genetic traits.
• Scientists identified four mutations in the Cyclic GMP-AMP synthase enzyme that enhance DNA repair, contributing to the Naked mole-rats longevity and cancer resistance.
• Comparative studies between Naked mole-rats and Mouse models show that the genetic adaptations in the former may hold keys to extending lifespans in other species.