'Molecular bodyguard' helps bacterial infections persist in hostile environments

Researchers at Umeå University discovered that the protein RfaH protects bacterial genes, enabling bacteria to survive within the human body, highlighting new avenues for combating infections.

• The study from Umeå University reveals that the protein RfaH acts as a molecular bodyguard, shielding bacterial genes that are vital for surviving the human bodys immune system and hostile environments.
• By protecting these genes, RfaH allows bacteria to persist against challenges like bile acid and nutrient scarcity, significantly contributing to the persistence of infections.
• Published in the journal mBio, this research uncovers the mechanisms of transcription (biology) regulation, emphasizing the role of proteins in bacterial survival strategies within the human body.