"Enteral Ventilation: Cincinnati's 'Butt Breathing' Advances to Human Trials"

Cincinnatis innovative enteral ventilation technique, which delivers oxygen rectally, has progressed to human trials in Japan, marking a potential breakthrough in treating blocked airways.

• The enteral ventilation method, developed by scientists at Cincinnati Childrens, successfully completed its initial human clinical trial in Japan, showcasing significant potential for respiratory support.
• Published on October 20, 2025, in the journal Med, the trial demonstrated that rectal oxygen delivery could effectively assist patients with compromised lung function.
• This groundbreaking technique earned an IgNobel prize in 2024, highlighting the unusual yet promising approach of using the rectum as a means for oxygen delivery to the circulatory system.